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Table 1 Characteristics of Cohort studies

From: The association between C-reactive protein and coronary artery calcification: a systematic review and meta-analysis

Study ID

Population

Place/Source

Age(years)

Sample Size/Follow-up

OR/HR/RR (CI95%)

Results

NOS

[3]

cardiovascular risk factors or atypical chest pain

South Korea

56.4 ± 7.2

1015 / 39 month

aHR:1.28 (1.04, 1.67)

Association in Univariate Analysis

Good

[26]

free of clinical cardiovascular disease

USA/MESA

61.8

6067/ 6.5 ± 3.5 years

RR: 0.97 (0.92, 1.02)

No association

Good

[40]

baseline zero CAC score

Taiwan

51.17 ± 8.24

830/4.55 ± 2.42 years

OR: 1.399 (0.923, 2.123)

No association

Good

[34]

Asymptomatic intermediate ASCVD risk factors

USA/EISNER

62.5 ± 8.3

1207/4 years

OR: 0.95

No association

Good

[35]

random sample from the general population

Denmark

55.39 ± 5.01

1006/ 5 years

IRR: 1.01 (0.96, 1.06)

No association

Good

[36]

with an enhanced risk for CAD

Germany

58.8 ± 10.0

94/1.9 ± 0.5 years

N/A

No association

Good

[37]

classified as low risk for CHD events

USA/MESA

60.4 ± 9.2

2620/2.5 years

OR: 1.07 (0.97, 1.18)

No association

Good

[38]

no history of signs of CHD, hypertension, inflammatory diseases, or allergies

United Kingdom

63.36 ± 5.9

466/ 3 years

OR: 0.99 (0.89, 1.10)

No association

Good

[39]

healthy asymptomatic

USA/PACC

47.9 ± 2.8

180/ 2 years

OR: 1.23 (0.73, 2.08)

No association

Good

  1. OR Odds Ratio, HR Hazard Ratio, N/A Not announced
  2. aUnadjusted