Serum PM20D1 levels in patients with idiopathic pulmonary arterial hypertension and its clinical significance

Table 3 Logistic regression of risk factors for death in IPAH patients

Variables	Wald	Odds ratio	95% CI	P
Age	0.649	0.972	0.906–1.042	0.421
BMI	0.991	2.281	0.450-11.577	0.320
Sex	0.944	0.853	0.619–1.176	0.331
6MWD	22.068	1.055	1.031–1.078	< 0.001
RA	7.437	0.531	0.337–0.837	0.006
RV	2.930	1.481	0.945–2.321	0.087
PAW	0.022	1.040	0.613–1.765	0.883
PAV	1.138	0.001	0.001-2106.658	0.286
TASPE	1.347	0.763	0.483–1.205	0.246
TASPV	6.226	12.416	1.717–89.801	0.013
PASP	0.137	1.059	0.783–1.431	0.711
MPAP	0.944	0.807	0.524–1.244	0.331
PCWP	3.686	0.311	0.094–1.025	0.055
PVR	4.809	0.551	0.323–0.939	0.028
PVRI	0.685	0.211	0.005–8.407	0.408
MRAP	1.017	0.483	0.118–1.986	0.313
TC	2.391	3.193	0.733–13.913	0.122
TG	0.001	1.004	0.032–31.602	0.998
HDL-C	3.308	7574.119	0.500-1.148E8	0.069
LDL-C	2.092	6.483	0.515–81.633	0.148
ALB	8.220	3.145	1.437–6.882	0.004
NT-proBNP	5.220	0.998	0.997-1.000	0.022
cTNT	2.401	0.795	0.595–1.063	0.121
PM20D1	8.958	20.579	2.840-149.112	0.003

BMI – body mass index; 6MWD – 6 min walking distance; RA – right atrial; RV – right ventricle; PAW – pulmonary artery width; PAV – pulmonary artery velocity; TAPSE – tricuspid annular plane systolic excursion; TASPV – tricuspid annular plane systolic excursion; PASP – pulmonary arterial systolic pressure; mPAP – mean pulmonary arterial pressure; PCWP – pulmonary capillary wedge pressure; PVR – pulmonary vascular resistance; PVRI – pulmonary vascular resistance index; mRAP – mean right atrial pressure; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol; TG – triglycerides; TC – total cholesterol; ALB – albumin; NT-ProBNP - N terminal pro B type natriuretic peptide; cTnT – cardiac troponin T; PM20D1 – Peptidase M20 domain containing 1.

ISSN: 1471-2261