Serum PM20D1 levels in patients with idiopathic pulmonary arterial hypertension and its clinical significance

Table 1 Demographic and clinical data of all subjects

Variable	Deceased group, n = 31	Survival group, n = 72	p
Age, y	52.87 ± 9.92	46.97 ± 11.86	0.017
Sex, female (%)	12 (38.7)	27 (37.5)	0.885
BMI	24.14 (20.30-28.36)	24.75 (19.95–28.10)	0.980
WHO-FC
I-II, n (%)	0 (0%)	23 (31.9)
III-IV, n (%)	31 (100%)	49 (68.1)
6MWD (m)	230.70 ± 53.56	333.95 ± 35.17	< 0.001
RA (mm)	51.47 (43.54–61.88)	44.99 (34.80-53.36)	< 0.001
RV (mm)	56.97 ± 4.30	58.57 ± 4.24	0.082
PAW (mm)	33.39 ± 2.96	33.23 ± 2.99	0.803
PAV (m/s)	0.67 ± 0.08	0.65 ± 0.86	0.424
TASPE (mm)	14.93 ± 2.43	14.47 ± 2.73	0.423
TASPV (cm/s)	7.41 (4.97–9.59)	9.66 (6.94–11.56)	< 0.001
PASP (mmHg)	86.67 ± 4.57	85.67 ± 4.96	0.340
MPAP (mmHg)	62.44 ± 5.12	60.12 ± 5.30	0.043
PCWP (mmHg)	11.47 (8.32–14.94)	9.43 (7.52–11.72)	< 0.001
PVR (wood)	20.95 ± 2.45	17.56 ± 2.38	< 0.001
PVRI (wood/m²)	2.67 ± 0.36	2.73 ± 0.47	0.554
MRAP (mmHg)	7.56 ± 1.76	7.69 ± 1.55	0.710

BMI – body mass index; 6MWD – 6 min walking distance; RA – right atrial; RV – right ventricle; PAW – pulmonary artery width; PAV – pulmonary artery velocity; TAPSE – tricuspid annular plane systolic excursion; TASPV – tricuspid annular plane systolic excursion; PASP – pulmonary arterial systolic pressure; mPAP – mean pulmonary arterial pressure; PCWP – pulmonary capillary wedge pressure; PVR – pulmonary vascular resistance; PVRI – pulmonary vascular resistance index; mRAP – mean right atrial pressure. Continuous data presented non-normal distribution were expressed by median (minimum to maximum) and analyzed by Mann-Whitney U test. Continuous data presented normal distribution were expressed by mean ± SD and analyzed by Student’s t test. Chi square test was used for rates.

ISSN: 1471-2261