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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: Inhibition of valve mesenchymal stromal cell calcium deposition by bFGF through alternative polyadenylation regulation of the CAT gene

Fig. 5

Catalase is one of the potential targets under the regulation of bFGF induced APA. A, UCSC genome browser track figure demonstrates all three samples under bFGF treatment has shortened APA event in CAT gene. B, RNA-seq and qPCR results of the distal APA expression level. ***: p < 0.001 C, qPCR results showed the proximal poly-A usage of CAT gene is not significantly altered. D, Western blot assays showed the protein expression of CAT is increased and OPN and RUNX2 are decreased in bFGF group. APA = alternative polyadenylation, CAT = catalase, OPN = Osteopontin, RUNX2 = Runt-related transcription factor-2

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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