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Table 2 Key imaging data in sinus rhythm versus atrial fibrillation groups

From: Is atrial fibrillation in HFpEF a distinct phenotype? Insights from multiparametric MRI and circulating biomarkers

 

Sinus rhythm

AF

P value*

Echocardiography data

 E wave (cm/s)

75 ± 27

92 ± 27

0.002

 E deceleration time (ms)

259 ± 78

211 ± 60

< 0.001

 Septal e’ (cm/s)

6.5 ± 4.6

6.6 ± 1.8

0.733

 Lateral e’ (cm/s)

7.7 ± 2.2

8.8. ± 2.6

0.104

 E:e’ ratio

12.9 ± 4.7

12.8 ± 4.7

0.858

CMR data

 LV EDVi (mL/m2)

71 ± 18

75 ± 18

0.378

 LV ESVi (mL/m2)

23 ± 10

28 ± 10

0.028

 LV SVi (mL/m2)

47 ± 11

47 ± 12

0.550

 LV EF (%)

68 ± 8

63 ± 8

0.002

 LVMi (g/m2)

60 ± 13

60 ± 15

0.461

 LVM/EDV (g/mL)

0.89 ± 0.20

0.82 ± 0.17

0.503

 GLS (%)

14.7 ± 2.4

13.6 ± 2.9

0.003

 GCS (%)

18.3 ± 2.8

15.7 ± 3.5

< 0.001

 Longitudinal PEDSR (s−1)

0.53 ± 0.17

0.73 ± 0.28

< 0.001

 Circumferential PEDSR (s−1)

0.67 ± 0.23

0.86 ± 0.33

0.002

 Maximum LAVi (mL/m2)

39 ± 15

61 ± 30

< 0.001

 Minimum LAVi (mL/m2)

20 ± 11

44 ± 27

< 0.001

 LAV/LV EDV

0.56 ± 0.17

0.81 ± 0.38

< 0.001

 LA EF (%)

51 ± 12

31 ± 15

< 0.001

 Presence of LGE, n (%)

34 (45)

29 (50)

0.360

  Presence of infarct, n (%)

11 (15)

11 (18)

0.382

  Presence of non-ischaemic LGE, n (%)

26 (35)

21 (35)

0.555

 Native T1 (ms)

1237 ± 63

1227 ± 84

0.879

 Extracellular Volume (%)

26.8 ± 4.1

28.4 ± 4.9

0.092

 Stress MBF (mL/min/g)

1.74 ± 0.70

1.57 ± 0.63

0.424

 Rest MBF (mL/min/g)

1.22 ± 0.45

0.95 ± 0.32

0.042

 MPR

1.66 ± 0.72

1.72 ± 0.64

0.722

  1. Data are presented as mean ± standard deviation or number (%) as appropriate. Abbreviations: AF atrial fibrillation; LV left ventricle; EDVi indexed end-diastolic volume; ESVi indexed end-systolic volume; SVi indexed stroke volume; EF ejection fraction; LVMi indexed left ventricular mass; LAVi indexed left atrial volume; GCS global circumferential strain; GLS global longitudinal strain; PEDSR peak early diastolic strain rate; LGE late gadolinium enhancement; MBF myocardial blood flow; MPR myocardial perfusion reserve. *ANCOVA with age, sex, ethnicity, BMI, diabetes status, systolic BP and eGFR as covariates. P value< 0.05 considered statistically significant and are highlighted in bold.