Fig. 1

miR-26a-5p and pyroptosis-associated proteins were up-regulated in PE-induced cardiac hypertrophy. (A): Representative images of cardiac hypertrophy, as shown by a-SMA immunofluorescence. The nucleus was stained with DAPI (blue). The scale bar shows 10 μm. (B): Cell surface area was measured using anti-SMA staining (green) under fluorescence microscopy. (C): The mRNA expression of miR-26a-5p was detected in PE-induced cardiac hypertrophy by RT-qPCR, (D-G): The proteins expression of miR-26a-5p, ACS, NLRP3, Caspase-1 were detected in PE-induced cardiac hypertrophy by Western blotting. (*: p-value < 0.05; **: p-value < 0.01; ***: p-value < 0.001.)