Skip to main content

Table 2 Clinical and biochemical characteristics by quartiles of serum adipsin levels

From: Circulating adipsin is associated with asymptomatic carotid atherosclerosis in obese adults

Variables

Serum adipsin level

P-value for trend§:

Q1

Q2

Q3

Q4

Sample size

120

121

122

120

 

Serum adipsin (ug/ml)

3.52 ± 0.61

4.53 ± 0.35

5.49 ± 0.44

7.96 ± 2.01

 < 0.001

Age (years)

53.0 ± 7.6

53.5 ± 7.0

54.0 ± 7.2

56.0 ± 6.5‡

0.007

Gender (male n, %)

32 (26.7)

33 (27.3)

33 (27.1)

32 (26.7)

0.990

BMI (kg/m2)

26.7 ± 2.8

27.1 ± 2.8

27.6 ± 3.0

27.6 ± 3.1†

0.036

Waist circumference (cm)

92.8 ± 6.6

93.6 ± 6.9

94.8 ± 6.9†

95.7 ± 6.9‡

0.007

Current smokers (n, %)

17(14.2)

16(13.2)

23(18.9)

18(15.0)

0.633

Systolic BP (mmHg)

128.1 ± 15.3

129.6 ± 17.3

128.8 ± 13.7

131.6 ± 18.3

0.705

Diastolic BP (mmHg)

77.2 ± 9.6

78.0 ± 10.9

78.0 ± 9.6

78.4 ± 10.3

0.821

Triglycerides (mmol/L)

1.50 (1.13–2.14)

1.57 (1.24–2.23)

1.60 (1.14–2.16)

1.70 (1.22–2.25)

0.268

Total cholesterol (mmol/L)

5.67 ± 1.06

5.71 ± 0.94

5.81 ± 0.99

5.84 ± 0.99

0.737

LDL- cholesterol (mmol/L)

3.66 ± 1.08

3.67 ± 0.92

3.89 ± 0.99

3.86 ± 0.90

0.248

HDL-cholesterol (mmol/L)

1.32 ± 0.26

1.29 ± 0.28

1.32 ± 0.23

1.31 ± 0.26

0.644

Fasting glucose (mmol/L)

5.64 ± 0.89

5.67 ± 1.03

5.50 ± 0.50

5.55 ± 0.53

0.183

2-h glucose (mmol/L)

8.37 ± 2.55

8.12 ± 2.49

7.63 ± 1.80†

7.83 ± 2.17†

0.027

HOMA-IR

2.97 (1.82- 4.06)

3.10 (2.14- 4.52)

2.58 (1.78- 3.64)

2.80 (2.08- 4.00)

0.015

Body fat mass(kg)

22.2 ± 4.7

22.9 ± 4.3

23.6 ± 4.8†

23.9 ± 4.9‡

0.017

Visceral fat (cm2)

116.3 ± 38.8

126.6 ± 50.7

124.0 ± 44.9

127.4 ± 39.0

0.302

CIMT (mm):

0.74 ± 0.16

0.76 ± 0.17

0.73 ± 0.15

0.71 ± 0.13†

0.009

Atherosclerotic plaque (n, %)

31 (25.8)

28 (23.1)

25 (20.5)

32 (26.7)

0.259

Asymptomatic carotid atherosclerosis*

51 (42.5)

60 (50.0)

54 (44.3)

44 (36.7)

0.017

  1. *Asymptomatic carotid atherosclerosis is defined as increased CIMT or presence of atherosclerotic plaque
  2. CIMT = Carotid intima-media thickness; BMI = body mass index; HOMA-IR = homeostasis model assessment of insulin resistance;
  3. Data are presented as the mean ± SD or median (interquartile range) or numbers (percentages)
  4. §Adjusted for age and gender
  5. †Adjusted P < 0.05compared with Q1 of serum adipsin
  6. ‡Adjusted P < 0.01compared with Q1 of serum adipsin