From: Circulating adipsin is associated with asymptomatic carotid atherosclerosis in obese adults
Variables | Serum adipsin level | P-value for trend§: | |||
---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | ||
Sample size | 120 | 121 | 122 | 120 | Â |
Serum adipsin (ug/ml) | 3.52 ± 0.61 | 4.53 ± 0.35 | 5.49 ± 0.44 | 7.96 ± 2.01 |  < 0.001 |
Age (years) | 53.0 ± 7.6 | 53.5 ± 7.0 | 54.0 ± 7.2 | 56.0 ± 6.5‡ | 0.007 |
Gender (male n, %) | 32 (26.7) | 33 (27.3) | 33 (27.1) | 32 (26.7) | 0.990 |
BMI (kg/m2) | 26.7 ± 2.8 | 27.1 ± 2.8 | 27.6 ± 3.0 | 27.6 ± 3.1†| 0.036 |
Waist circumference (cm) | 92.8 ± 6.6 | 93.6 ± 6.9 | 94.8 ± 6.9†| 95.7 ± 6.9‡ | 0.007 |
Current smokers (n, %) | 17(14.2) | 16(13.2) | 23(18.9) | 18(15.0) | 0.633 |
Systolic BP (mmHg) | 128.1 ± 15.3 | 129.6 ± 17.3 | 128.8 ± 13.7 | 131.6 ± 18.3 | 0.705 |
Diastolic BP (mmHg) | 77.2 ± 9.6 | 78.0 ± 10.9 | 78.0 ± 9.6 | 78.4 ± 10.3 | 0.821 |
Triglycerides (mmol/L) | 1.50 (1.13–2.14) | 1.57 (1.24–2.23) | 1.60 (1.14–2.16) | 1.70 (1.22–2.25) | 0.268 |
Total cholesterol (mmol/L) | 5.67 ± 1.06 | 5.71 ± 0.94 | 5.81 ± 0.99 | 5.84 ± 0.99 | 0.737 |
LDL- cholesterol (mmol/L) | 3.66 ± 1.08 | 3.67 ± 0.92 | 3.89 ± 0.99 | 3.86 ± 0.90 | 0.248 |
HDL-cholesterol (mmol/L) | 1.32 ± 0.26 | 1.29 ± 0.28 | 1.32 ± 0.23 | 1.31 ± 0.26 | 0.644 |
Fasting glucose (mmol/L) | 5.64 ± 0.89 | 5.67 ± 1.03 | 5.50 ± 0.50 | 5.55 ± 0.53 | 0.183 |
2-h glucose (mmol/L) | 8.37 ± 2.55 | 8.12 ± 2.49 | 7.63 ± 1.80†| 7.83 ± 2.17†| 0.027 |
HOMA-IR | 2.97 (1.82- 4.06) | 3.10 (2.14- 4.52) | 2.58 (1.78- 3.64) | 2.80 (2.08- 4.00) | 0.015 |
Body fat mass(kg) | 22.2 ± 4.7 | 22.9 ± 4.3 | 23.6 ± 4.8†| 23.9 ± 4.9‡ | 0.017 |
Visceral fat (cm2) | 116.3 ± 38.8 | 126.6 ± 50.7 | 124.0 ± 44.9 | 127.4 ± 39.0 | 0.302 |
CIMT (mm): | 0.74 ± 0.16 | 0.76 ± 0.17 | 0.73 ± 0.15 | 0.71 ± 0.13†| 0.009 |
Atherosclerotic plaque (n, %) | 31 (25.8) | 28 (23.1) | 25 (20.5) | 32 (26.7) | 0.259 |
Asymptomatic carotid atherosclerosis* | 51 (42.5) | 60 (50.0) | 54 (44.3) | 44 (36.7) | 0.017 |