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Table 1 Clinical and biochemical characteristics of obese subjects

From: Circulating adipsin is associated with asymptomatic carotid atherosclerosis in obese adults

Variables

Increased CIMT

Atherosclerotic plaque

Asymptomatic carotid atherosclerosis*

Yes

No

P-value§

Yes

No

P-value§

Yes

No

P-value§

Sample size

138

345

 

116

367

 

209

274

 

Age (years)

56.0 ± 6.2

53.4 ± 7.4

 < 0.001

58.1 ± 6.1

52.9 ± 7.0

 < 0.001

56.7 ± 6.3

52.2 ± 7.2

 < 0.001

Gender (male n, %)

56(40.6)

74(21.5)

 < 0.001

41(35.3)

89(24.3)

0.019

75(35.9)

55(20.1)

 < 0.001

BMI (kg/m2)

27.6 ± 2.9

27.1 ± 2.9

0.081

26.9 ± 3.0

27.3 ± 2.9

0.225

27.3 ± 3.0

27.2 ± 2.9

0.599

Waist circumference (cm)

95.1 ± 7.1

93.9 ± 6.8

0.755

94.0 ± 6.5

94.3 ± 7.0

0.079

94.6 ± 6.9

93.9 ± 6.9

0.550

Current smokers (n, %)

31(22.5)

43(12.5)

0.006

20(17.2)

54(14.7)

0.511

41(19.6)

33(12.0)

0.022

Systolic BP (mmHg)

134.8 ± 17.5

127.4 ± 15.2

0.001

133.7 ± 18.5

128.2 ± 15.2

0.148

132.7 ± 17.6

127.1 ± 14.7

0.084

Diastolic BP (mmHg)

80.0 ± 10.5

77.1 ± 9.8

0.052

78.7 ± 10.6

77.7 ± 9.9

0.733

78.7 ± 10.4

77.3 ± 9.8

0.594

Triglycerides (mmol/L)

1.83 (1.31–2.35)

1.51 (1.13–2.12)

0.682

1.65 (1.19–2.14)

1.58 (1.17–2.20)

0.780

1.70 (1.20–2.23)

1.54 (1.12–2.14)

0.591

Total cholesterol (mmol/L)

6.07 ± 1.07

5.64 ± 0.94

 < 0.001

6.03 ± 1.10

5.67 ± 0.95

0.014

5.96 ± 1.04

5.61 ± 0.94

0.003

LDL-cholesterol (mmol/L)

4.00 ± 1.00

3.68 ± 0.96

0.009

4.06 ± 1.10

3.68 ± 0.92

0.014

3.96 ± 0.99

3.63 ± 0.94

0.012

HDL-cholesterol (mmol/L)

1.28 ± 0.22

1.32 ± 0.27

0.542

1.30 ± 0.24

1.31 ± 0.26

0.687

1.28 ± 0.23

1.33 ± 0.27

0.204

Fasting glucose (mmol/L)

5.75 ± 0.91

5.53 ± 0.70

0.032

5.65 ± 1.01

5.57 ± 0.68

0.911

5.65 ± 0.82

5.55 ± 0.74

0.789

2-h glucose (mmol/L)

8.07 ± 2.34

7.95 ± 2.26

0.734

8.05 ± 2.59

7.97 ± 2.18

0.702

7.97 ± 2.29

8.00 ± 2.28

0.406

HOMA-IR

2.91 (2.26–3.87)

2.83 (1.84–4.08)

0.147

2.62 (1.90–4.07)

2.97 (1.95–4.01)

0.736

2.72 (1.97–3.86)

2.98 (1.93–4.11)

0.965

Serum adipsin (ug/ml)

5.13 ± 1.43

5.47 ± 2.14

0.002

5.50 ± 2.20

5.33 ± 1.89

0.475

5.28 ± 1.88

5.44 ± 2.04

0.004

Body fat mass(kg)

22.9 ± 5.2

23.2 ± 4.5

0.432

22.3 ± 4.7

23.4 ± 4.7

0.228

5.29 ± 1.88

5.44 ± 2.04

0.876

Visceral fat (cm2)

144.3 ± 45.7

115.2 ± 40.1

 < 0.001

127.6 ± 42.5

122.3 ± 44.1

0.159

134.2 ± 44.8

115.4 ± 41.2

0.036

  1. *Asymptomatic carotid atherosclerosis is defined as increased CIMT or presence of atherosclerotic plaque
  2. CIMT = Carotid intima-media thickness; BMI = body mass index; HOMA-IR = homeostasis model assessment of insulin resistance;
  3. Data are presented as the mean ± SD or median (interquartile range) or numbers (percentages)
  4. §Adjusted for age and gender
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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