Table 6 Sensitivity, specificity, positive predictive value and negative predictive value for positive FH as defined by the SB, US MEDPED and JFHMC definitions against the DLCC definition
Definitions | DLCC | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Yes FH | No FH | TOTAL | Sensitivity(%) | Specificity (%) | PPV (%) | NPV (%) | Efficiency (%) | p-value† | |
Simon Broome | |||||||||
Positive FH | 212 | 4 | 216 | 51.1 | 98.8 | 98.1 | 62.3 | 28.6 | <0.001* |
Negative FH | 203 | 336 | 539 | ||||||
TOTAL | 415 | 340 | 755 | ||||||
US MEDPED | |||||||||
Positive FH | 105 | 2 | 107 | 25.3 | 99.4 | 98.1 | 56.1 | 14.1 | <0.001* |
Negative FH | 310 | 338 | 648 | ||||||
TOTAL | 415 | 340 | 755 | ||||||
JFHMC | |||||||||
Positive FH | 195 | 4 | 199 | 47.0 | 98.8 | 97.9 | 60.4 | 26.4 | <0.001* |
Negative FH | 220 | 336 | 556 | ||||||
TOTAL | 415 | 340 | 755 | ||||||