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Table 4 Severity of CAD/ STEMI, treatment modalities and outcome according to SES-group

From: Socially disadvantaged city districts show a higher incidence of acute ST-elevation myocardial infarctions with elevated cardiovascular risk factors and worse prognosis

 

G1 (n = 519)

G2 (n = 813)

G3 (n = 1554)

G4 (n = 576)

p-value

Severity of myocardial infarction

 Number of coronary vesssels affected ±SD

1.99 ± 0.8

1.94 ± 0.8

1.91 ± 0.8

1.84 ± 0.8

0.09

 Cardiogenic shock (%)

12.1

13.1

12.0

12.4

0.8

 Prehospital CPR (%)

10.9

11.3

10.8

10.3

0.5

 Subacute MI(%) a

19.3

23.9

20.5

19.9

0.8

 Mean peak CK (U/l) ± SD

1599 ± 1679

1838 ± 2019

1913 ± 2188

2025 ± 2167

<0.01

 Peak CK > 3000 U/l (%)

13.7

20.5

20.9

23.3

<0.01

 Post AMI LVEF in % ± SD

49.6 ± 9

48.9 ± 10

48.4 ± 11

47.5 ± 10

<0.01

 LVEF <40% (%)

10.4

13.8

15.8

16.3

0.01

Treatment modalitites

 Primary PCI (%)

89.0

91.1

89.9

90.9

0.9

 CABG (%)

6.1

3.9

4.8

3.4

0.14

 Conservative therapy regimen (%)

4.8

4.9

5.2

5.7

0.8

 Door to balloon time in min (median ± SD)

48 ± 32

43 ± 44.5

46 ± 40

44 ± 41

0.74

 GP2b3a-Inhibitors (%)

70

67

66

70

0.7

 ASA (at discharge) (%)

94

96

94

95

0.64

 ADP-Antagon. (ad) (%)

90

90.5

90

94

0.23

 Beta-blockers (ad) (%)

83

84

80

84

0.25

 Statins (ad) (%)

86

87

87

86

0.9

 ACE/ATR-Inhibitors (ad) (%)

77

80

79

79

0.9

Outcome

 Mortality <72 h (%)

3.9

3.6

3.9

4.2

0.71

 Inhospital mortality (%)

8.8

7.6

7.9

8.1

0.71

 1-year-mortality (%)

15.7

15.1

14.9

16.3

0.9

 1-year-MACCE (%)

19.2

19.5

19.1

20.4

0.8

 5-year-mortality (%)

23.9

27.7

25.7

28.3

0.46

 5-year-MACCE (%)

30.8

35.7

36.0

41.1

0.02

  1. asubacute MI was defined as onset of symptoms >12 h before admission to PCI- center and/or signs of subacute STEMI in initial ECG